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Dextromethorphan Hydrobromide

Generic / Active Ingredient
Cough suppressant 13 brands 13 manufacturers Syrup

What is Dextromethorphan Hydrobromide used for?

Non-productive cough

13 Dextromethorphan Hydrobromide brands in Bangladesh

Compare prices across every brand of Dextromethorphan Hydrobromide and pick the most affordable option.

Brand Strength Form Manufacturer Price
Brofex 10 mg/5 ml Syrup Square Pharmaceuticals Ltd. ৳ 40.13
Coldflu 10 mg/5 ml Syrup Amico Laboratories Ltd. ৳ 23.00
D-cough 10 mg/5 ml Syrup Opsonin Pharma Ltd. ৳ 35.11
Dexpofen 10 mg/5 ml Syrup Eskayef Pharmaceuticals Ltd. ৳ 40.00
Dexsol 10 mg/5 ml Syrup Gaco Pharmaceuticals Ltd. ৳ 35.11
Dextromethorphan 10 mg/5 ml Syrup Beximco Pharmaceuticals Ltd. ৳ 35.00
Dixar 10 mg/5 ml Syrup ACI Limited ৳ 40.00
Drikof 10 mg/5 ml Syrup Chemist Laboratories Ltd. ৳ 40.00
Exophan 10 mg/5 ml Syrup Apollo Pharmaceutical Ltd. ৳ 38.00
Leocof 10 mg/5 ml Syrup Leon Pharmaceuticals Ltd. ৳ 40.00
Metodex 10 mg/5 ml Syrup Ad-din Pharmaceuticals Ltd. ৳ 30.00
Tomephen 10 mg/5 ml Syrup Incepta Pharmaceuticals Ltd. ৳ 40.00
Tussidex 10 mg/5 ml Syrup UniMed UniHealth ৳ 23.00

Dextromethorphan Hydrobromide — Clinical Information

Indication DetailsView
Dextromethorphan is indicated in Chronic dry cough or unproductive cough; Acute dry cough which is interfering with normal function or sleep.
Therapeutic ClassView
Cough suppressant
PharmacologyView
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
DosageView
Adults and Children over 12 years: 15 to 30 mg three to four times per day. However, 60 mg doses up to four times per day have been used without increased side effects.
Children between 6 and 12 years: 5-15 mg up to four times per day.
Children between 2 and 6 years: 2.5-5 mg up to four times per day.
Side EffectsView
Adverse effects with Dextromethorphan are rare, but nausea and dizziness sometimes occur. The drug produces no analgesia or addiction and little or no CNS depression. Excitation, confusion and respiratory depression may occur after overdosage.
ContraindicationsView
Hypersensitivity to Dextromethorphan or any other component.
PrecautionsView
Do not use Dextromethorphan to control a cough that is associated with smoking, asthma, or emphysema, or a cough that is productive (produces sputum or phlegm).
InteractionsView
The following medicines should be taken carefully while concomitantly use with Dextromethorphan: Amiodarone, Fluoexetine, Quinidine, CNS depressants and Monoamine oxidase (MAO) inhibitors.
Pregnancy & LactationView
Pregnancy: Adequate and well-controlled studies in human have not been done. However, Dextromethorphan has not been reported to cause birth defects.

Lactation: It is not known whether dextromethorphan passes into breast milk. However, Dextromethorphan has not been reported to cause problems in nursing babies.
Overdose EffectsView
Symptoms: In mild overdose, tachycardia, hypertension, vomiting, mydriasis, diaphoresis, nystagmus, euphoria, loss of motor coordination, and giggling; in moderate intoxication, in addition to those listed above, hallucinations and a plodding ataxic gait; in severely intoxication, agitation or somnolence.

Management: treatment is symptomatic and supportive. Naloxone may be useful in reversing toxicity.
Storage ConditionsView
Store at 15-30° C