Dixar
Dextromethorphan Hydrobromide → (13 brands)
100 ml bottle
৳ 40.00
ACI Limited
Drug Class
Cough suppressant
Indication
Non-productive cough
Dosage Form
Syrup
Manufacturer
ACI Limited
Compare Alternate Brands
Same generic (Dextromethorphan Hydrobromide), 10 mg/5 ml, Syrup — 12 alternate brands available.
Brofex
Square Pharmaceuticals Ltd.
৳ 40.13
100 ml bottle
Lowest
Coldflu
Amico Laboratories Ltd.
৳ 23.00
100 ml bottle
D-cough
Opsonin Pharma Ltd.
৳ 35.11
100 ml bottle
Dexpofen
Eskayef Pharmaceuticals Ltd.
৳ 40.00
100 ml bottle
Dexsol
Gaco Pharmaceuticals Ltd.
৳ 35.11
100 ml bottle
Dextromethorphan
Beximco Pharmaceuticals Ltd.
৳ 35.00
100 ml bottle
Indication DetailsView
Dextromethorphan is indicated in Chronic dry cough or unproductive cough; Acute dry cough which is interfering with normal function or sleep.
Therapeutic ClassView
Cough suppressant
PharmacologyView
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
DosageView
Adults and Children over 12 years: 15 to 30 mg three to four times per day. However, 60 mg doses up to four times per day have been used without increased side effects.
Children between 6 and 12 years: 5-15 mg up to four times per day.
Children between 2 and 6 years: 2.5-5 mg up to four times per day.
Children between 6 and 12 years: 5-15 mg up to four times per day.
Children between 2 and 6 years: 2.5-5 mg up to four times per day.
Side EffectsView
Adverse effects with Dextromethorphan are rare, but nausea and dizziness sometimes occur. The drug produces no analgesia or addiction and little or no CNS depression. Excitation, confusion and respiratory depression may occur after overdosage.
ContraindicationsView
Hypersensitivity to Dextromethorphan or any other component.
PrecautionsView
Do not use Dextromethorphan to control a cough that is associated with smoking, asthma, or emphysema, or a cough that is productive (produces sputum or phlegm).
InteractionsView
The following medicines should be taken carefully while concomitantly use with Dextromethorphan: Amiodarone, Fluoexetine, Quinidine, CNS depressants and Monoamine oxidase (MAO) inhibitors.
Pregnancy & LactationView
Pregnancy: Adequate and well-controlled studies in human have not been done. However, Dextromethorphan has not been reported to cause birth defects.
Lactation: It is not known whether dextromethorphan passes into breast milk. However, Dextromethorphan has not been reported to cause problems in nursing babies.
Lactation: It is not known whether dextromethorphan passes into breast milk. However, Dextromethorphan has not been reported to cause problems in nursing babies.
Overdose EffectsView
Symptoms: In mild overdose, tachycardia, hypertension, vomiting, mydriasis, diaphoresis, nystagmus, euphoria, loss of motor coordination, and giggling; in moderate intoxication, in addition to those listed above, hallucinations and a plodding ataxic gait; in severely intoxication, agitation or somnolence.
Management: treatment is symptomatic and supportive. Naloxone may be useful in reversing toxicity.
Management: treatment is symptomatic and supportive. Naloxone may be useful in reversing toxicity.
Storage ConditionsView
Store at 15-30° C