Tobramycin (Ophthalmic)
Generic / Active Ingredient
What is Tobramycin (Ophthalmic) used for?
Ocular infections
26 Tobramycin (Ophthalmic) brands in Bangladesh
Compare prices across every brand of Tobramycin (Ophthalmic) and pick the most affordable option.
| Brand | Strength | Form | Manufacturer | Price |
|---|---|---|---|---|
| Cinarex | 0.30% | Ophthalmic Solution | Beximco Pharmaceuticals Ltd. | ৳ 100.00 |
| Eytob | 0.30% | Ophthalmic Solution | Navana Pharmaceuticals Ltd. | ৳ 95.00 |
| Gentob | 0.30% | Ophthalmic Ointment | General Pharmaceuticals Ltd. | ৳ 80.00 |
| Gentob | 0.30% | Ophthalmic Solution | General Pharmaceuticals Ltd. | ৳ 100.00 |
| Intobac | 0.30% | Ophthalmic Solution | Incepta Pharmaceuticals Ltd. | ৳ 90.00 |
| Ocutob | 0.30% | Ophthalmic Solution | Globe Pharmaceuticals Ltd. | ৳ 85.00 |
| T-Drop | 0.30% | Ophthalmic Solution | Reman Drug Laboratories Ltd. | ৳ 90.00 |
| T-Mycin | 0.30% | Ophthalmic Ointment | Aristopharma Ltd. | ৳ 80.00 |
| T-Mycin | 0.30% | Ophthalmic Solution | Aristopharma Ltd. | ৳ 100.00 |
| Tobam | 0.30% | Ophthalmic Solution | Monicopharma Ltd. | ৳ 85.00 |
| Tobi | 0.30% | Ophthalmic Solution | Asiatic Laboratories Ltd. | ৳ 80.00 |
| Tobirax | 0.30% | Ophthalmic Ointment | Gaco Pharmaceuticals Ltd. | ৳ 60.00 |
| Tobirax | 0.30% | Ophthalmic Solution | Gaco Pharmaceuticals Ltd. | ৳ 90.27 |
| Tobrabac | 0.30% | Ophthalmic Ointment | Popular Pharmaceuticals Ltd. | ৳ 60.00 |
| Tobrabac | 0.30% | Ophthalmic Solution | Popular Pharmaceuticals Ltd. | ৳ 85.00 |
| Tobracin | 0.30% | Ophthalmic Solution | Opso Saline Ltd. | ৳ 90.01 |
| Tobracin | 0.30% | Ophthalmic Ointment | Opso Saline Ltd. | ৳ 30.11 |
| Tobram | 0.30% | Ophthalmic Solution | Pacific Pharmaceuticals Ltd. | ৳ 100.00 |
| Tobramin | 0.30% | Ophthalmic Solution | Nipa Pharmaceuticals Ltd. | ৳ 90.01 |
| Tobrel | 0.30% | Ophthalmic Solution | Healthcare Pharmaceuticals Ltd. | ৳ 100.00 |
| Tomin | 0.30% | Ophthalmic Solution | Kemiko Pharmaceuticals Ltd. | ৳ 100.00 |
| Tomycin | 0.30% | Ophthalmic Ointment | Ibn Sina Pharmaceuticals Ltd. | ৳ 55.00 |
| Tomycin | 0.30% | Ophthalmic Solution | Ibn Sina Pharmaceuticals Ltd. | ৳ 90.00 |
| Torcin | 0.30% | Ophthalmic Ointment | Opsonin Pharma Ltd. | ৳ 70.00 |
| Torcin | 0.30% | Ophthalmic Solution | Opsonin Pharma Ltd. | ৳ 90.00 |
| Xitob | 0.30% | Ophthalmic Solution | Biopharma Laboratories Ltd. | ৳ 90.00 |
Indication DetailsView
Tobramycin is a topical antibiotic indicated in the treatment of external bacterial infections of the eye caused by susceptible organisms. Such as,
Gram-positive bacteria: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus spp. of group A beta-hemolytic and some nonhemolytic species.
Gram-negative bacteria: E.coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Klebsiella spp., Proteusmirabillis, Proteus vulgaris, Haemophilus influenzae, Morganella morganii, Acinetobacter calcoaceticus, Providentia, Serratia, Salmonella spp and some strains of Neisseria.
Gram-positive bacteria: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus spp. of group A beta-hemolytic and some nonhemolytic species.
Gram-negative bacteria: E.coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Klebsiella spp., Proteusmirabillis, Proteus vulgaris, Haemophilus influenzae, Morganella morganii, Acinetobacter calcoaceticus, Providentia, Serratia, Salmonella spp and some strains of Neisseria.
Therapeutic ClassView
Ophthalmic antibacterial drugs
PharmacologyView
Like other aminoglycosides, the bactericidal activity of Tobramycin is taken up into sensitive bacterial cells by an active transport process. Within the cell Tobramycin bind to the 30s, and to some extent to the 50s subunits of the bacterial ribosome, inhibiting protein synthesis and generating errors in the transcription of the genetic code. The manner in which cell death is brought about is imperfectly understood, and other mechanisms may contribute, including effects on membrane permeability.
DosageView
Ophthalmic ointment:
- In mild to moderate infection, apply a small amount 2-3 times daily into the conjunctival sac(s).
- In severe cases of infection, apply a small amount 3-4 times daily into the conjunctival sac(s) until improvement is obtained, then reduce the dose gradually.
- In mild to moderate infections: Instill 1or 2 drops into the affected eye(s) every 4 hours.
- In severe infections: Instill 2 drops into the affected eye(s) every hour until improvement is observed.
Side EffectsView
The most frequent side effect of Tobramycin ophthalmic solution is localized ocular toxicity, conjunctival erythema, hypersensitivity including lid itching and swelling.
ContraindicationsView
It is contraindicated in patients who are hypersensitive to Tobramycin or any of the ingredients of the preparation.
PrecautionsView
Minor sensitivity may occur to topically applied aminoglycosides in some patients. If a sensitivity reaction occurs, discontinue use. Prolonged use may result in overgrowth of nonsusceptible organisms and fungi.
InteractionsView
Care should be exercised when tobramycin is given to patients receiving other drugs with neuromauscular blocking agents or ototoxic.
Pregnancy & LactationView
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should only be used during pregnancy, if the potential benefits outweigh the possible risk to the fetus. Drug may excreted into human milk. A decision should be made whether to discontinue nursing or to taking the drug.
Overdose EffectsView
Sign and symptoms of overdose may be similar to side effects as described above.
Storage ConditionsView
Protect from light, store in cool (below 25°C) & dry place. Keep out of reach of children. Used within 4 weeks after first opening.