Rasagiline
Generic / Active Ingredient
What is Rasagiline used for?
Parkinson’s disease
6 Rasagiline brands in Bangladesh
Compare prices across every brand of Rasagiline and pick the most affordable option.
| Brand | Strength | Form | Manufacturer | Price |
|---|---|---|---|---|
| Ragil | 1 mg | Tablet | Eskayef Pharmaceuticals Ltd. | ৳ 20.00 |
| Ragil | 0.5 mg | Tablet | Eskayef Pharmaceuticals Ltd. | ৳ 15.00 |
| Rasagil | 1 mg | Tablet | Healthcare Pharmaceuticals Ltd. | ৳ 20.00 |
| Rasagil | 0.5 mg | Tablet | Healthcare Pharmaceuticals Ltd. | ৳ 15.00 |
| Rasalet | 1 mg | Tablet | Square Pharmaceuticals Ltd. | ৳ 20.00 |
| Rasalet | 0.5 mg | Tablet | Square Pharmaceuticals Ltd. | ৳ 15.00 |
Indication DetailsView
Rasagiline is indicated for the treatment of the signs and symptoms of idiopathic Parkinson's disease as initial monotherapy, and as adjunct therapy to dopamine agonists or to levodopa.
Therapeutic ClassView
Antiparkinson drugs
PharmacologyView
Rasagiline is a potent, irreversible, selective MAO-B inhibitor that effectively crosses the blood brain barrier after oral administration. The precise mechanisms of action of Rasagiline are unknown. One mechanism is believed to be related to its MAO-B inhibitory activity, which causes an increase in extracellular levels of dopamine in the brain. The elevated dopamine level and subsequent increased dopaminergic activity are likely to mediate Rasagiline's beneficial effects.
DosageView
Monotherapy: Rasagiline 1 mg once daily
As adjunct without Levodopa: Rasagiline 1 mg once daily
As adjunct to Levodopa: Rasagiline 0.5 mg once daily
As adjunct without Levodopa: Rasagiline 1 mg once daily
As adjunct to Levodopa: Rasagiline 0.5 mg once daily
Side EffectsView
Common side effects of Rasagiline include: dizziness, spinning sensation, joint pain, headache, heartburn, nausea, muscle pain etc.
ContraindicationsView
Rasagiline is contraindicated for use with meperidine, tramadol, methadone, propoxyphene and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome.
PrecautionsView
Exacerbation of hypertension may occur during treatment with Rasagiline. Medication adjustment may be necessary if elevation of blood pressure is sustained. Dose should not exceed 0.5 mg once daily for patients with mild hepatic impairment or taking concomitant Ciprofloxacin or other CYP1A2 inhibitors.
InteractionsView
Concomitant use of Rasagiline with meperidine, dextromethorphan, antidepressants is not recommended.
Pregnancy & LactationView
Pregnancy Category C. Rasagiline should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk. So, caution should be exercised when administered to a nursing woman.
Pediatric UsageView
Pediatric use: The safety and effectiveness in pediatric patients have not been established.
Storage ConditionsView
Store below 30° c, protected from light and moisture. Keep all the medicines out of reach of children.