Ofloxacin (Ophthalmic)
Generic / Active Ingredient
What is Ofloxacin (Ophthalmic) used for?
Otitis externa
2 Ofloxacin (Ophthalmic) brands in Bangladesh
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Indication DetailsView
Eye: It is indicated for the treatment of external ocular infections such as acute & sub-acute conjunctivitis, keratitis, kerato-conjunctivitis, blepharo-conjunctivitis, blepharitis, corneal ulcer and pre-operative prophylaxis in ocular surgery.
Ear: It is indicated for the treatment of external ear infections (otitis externa) and certain middle ear infections (otitis media).
Ear: It is indicated for the treatment of external ear infections (otitis externa) and certain middle ear infections (otitis media).
Therapeutic ClassView
4-Quinolone preparations, Ophthalmic antibacterial drugs
PharmacologyView
Ofloxacin is a synthetic 4-fluoroquinolone antibacterial agent with bactericidal activity against a wide range of Gram-negative and Gram-positive organisms. Ofloxacin is thought to exert bactericidal effect by inhibiting DNA gyrase, an essential enzyme that is a critical catalyst in the duplication, transcription and repair of bacterial DNA.
DosageView
Eye: Instill 1 drop in the affected eye(s) every 2 to 4 hours for the first two days and then 4 times daily. The length of treatment should not exceed ten days.
Ear: Instill 1-2 drops in the affected ear(s) twice daily or as needed.
Ear: Instill 1-2 drops in the affected ear(s) twice daily or as needed.
Side EffectsView
Eye: Transient ocular irritation, burning, stinging, redness, itching or photophobia have been reported.
Ear: Mild irritation or mild discomfort in the ear may occur. Symptoms of an allergic reaction include rash, itching, swelling or trouble breathing.
Ear: Mild irritation or mild discomfort in the ear may occur. Symptoms of an allergic reaction include rash, itching, swelling or trouble breathing.
ContraindicationsView
It is contraindicated in patients who are hypersensitive to Ofloxacin or any other component of this preparation.
PrecautionsView
Prolonged use of eye drops & ear drops may result in overgrowth of non-susceptible organisms and secondary infection respectively.
Pregnancy & LactationView
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in lactation: It is not known whether Ofloxacin is excreted in human milk. Cautions should be taken when Ofloxacin eye & ear drops is administered during lactation.
Use in lactation: It is not known whether Ofloxacin is excreted in human milk. Cautions should be taken when Ofloxacin eye & ear drops is administered during lactation.