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Fluphenazine + Nortriptyline

Generic / Active Ingredient
Combined anxiolytics & anti-depressant drugs 10 brands 10 manufacturers Tablet

What is Fluphenazine + Nortriptyline used for?

Gastric problems

10 Fluphenazine + Nortriptyline brands in Bangladesh

Compare prices across every brand of Fluphenazine + Nortriptyline and pick the most affordable option.

Brand Strength Form Manufacturer Price
Amival 0.5 mg+10 mg Tablet Amico Laboratories Ltd. ৳ 0.80
Apresin 0.5 mg+10 mg Tablet Beximco Pharmaceuticals Ltd. ৳ 1.05
Euphor 0.5 mg+10 mg Tablet Biopharma Laboratories Ltd. ৳ 0.80
Flutrip 0.5 mg+10 mg Tablet General Pharmaceuticals Ltd. ৳ 0.71
Fresh 0.5 mg+10 mg Tablet Nipa Pharmaceuticals Ltd. ৳ 0.80
Monitol 0.5 mg+10 mg Tablet Skylab Pharmaceuticals Ltd. ৳ 0.80
Mudibak 0.5 mg+10 mg Tablet Rephco Pharmaceuticals Ltd. ৳ 0.75
Norflu 0.5 mg+10 mg Tablet ACME Laboratories Ltd. ৳ 1.06
Norzin 0.5 mg+10 mg Tablet Aristopharma Ltd. ৳ 1.05
Permival 0.5 mg+10 mg Tablet Opsonin Pharma Ltd. ৳ 1.00

Fluphenazine + Nortriptyline — Clinical Information

Indication DetailsView
This is indicated in
  • Mild to moderate mixed anxiety/depression
  • Emotional disturbance
  • Sleep disorder
  • Gastric problems
Therapeutic ClassView
Combined anxiolytics & anti-depressant drugs
PharmacologyView
Nortriptyline hydrochloride is a tricyclic antidepressant. Nortriptyline inhibits the uptake of norepinephrine and serotonin at nerve terminals. In contrast to its parent compound amitriptyline which is equally potent in inhibiting the uptake of norepinephrine and serotonin, Nortriptyline has a greater effect on norepinephrine reuptake than on serotonin reuptake.

Fluphenazine is a tranquilizer of the phenothiazine type with piperazine side chain. Fluphenazine primarily acts as a neuroleptic drug whose main therapeutic effect is believed to reside in potent dopamine (specially D2) receptor antagonism.
DosageView
Adults: One tablet 2 to 3 times daily.
Side EffectsView
Tardive dyskinesias have been reported in phenothiazine therapy; usually after prolonged courses given at doses adequately to control psychotic illness. Blood dyscrasia, Malignant Neuroleptic syndrome and sudden death have been reported rarely. Agranulocytosis is a rare but potentially fatal adverse effect of Nortriptyline Hydrochloride.
ContraindicationsView
It is contraindicated in :
  • History of gradual epilepsy or organic brain damage
  • Blood dyscrasia
  • Severe cardiac insufficiency
  • Renal or liver damage
  • Patients taking monoamine oxidase inhibitor (MAOI)
  • Younger children
  • Hypersensitivity to any component of the preparation
PrecautionsView
Precautions should be taken in patients with glaucoma, prostate enlargement, cardiac failure and myocardial infarction, and in concurrent administration with CNS depressants. The drug may impair alertness and abilities to drive a car or operate machinery.
InteractionsView
Interactions with barbiturates, alcohol, and narcotic drugs may occur, so central depressants should be administered with caution.
Pregnancy & LactationView
The safety in human pregnancy has not been yet established. The use of this drug in lactation is not recommended, as it is excreted in breast milk.
Storage ConditionsView
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.