Diphenhydramine Hydrochloride
Generic / Active Ingredient
What is Diphenhydramine Hydrochloride used for?
Wheezing
13 Diphenhydramine Hydrochloride brands in Bangladesh
Compare prices across every brand of Diphenhydramine Hydrochloride and pick the most affordable option.
| Brand | Strength | Form | Manufacturer | Price |
|---|---|---|---|---|
| Adryl | 10 mg/5 ml | Syrup | Square Pharmaceuticals Ltd. | ৳ 40.13 |
| Bena-Flu | 10 mg/5 ml | Syrup | Cosmic Pharma Ltd. | ৳ 35.00 |
| Didryl | 10 mg/5 ml | Syrup | Gaco Pharmaceuticals Ltd. | ৳ 45.31 |
| Difin | 10 mg/5 ml | Syrup | Nipa Pharmaceuticals Ltd. | ৳ 40.00 |
| Dorenta | 50 mg | Tablet | Eskayef Pharmaceuticals Ltd. | ৳ 2.50 |
| Dorenta | 10 mg/5 ml | Syrup | Eskayef Pharmaceuticals Ltd. | ৳ 40.00 |
| Pedeamin | 10 mg/5 ml | Syrup | Beximco Pharmaceuticals Ltd. | ৳ 45.00 |
| Pedilar | 10 mg/5 ml | Syrup | Popular Pharmaceuticals Ltd. | ৳ 45.17 |
| Pediphen | 10 mg/5 ml | Syrup | Somatec Pharmaceuticals Ltd. | ৳ 38.00 |
| Pedryl | 10 mg/5 ml | Syrup | Oyster Pharmaceuticals Ltd. | ৳ 20.00 |
| Phenadryl | 10 mg/5 ml | Syrup | ACME Laboratories Ltd. | ৳ 40.00 |
| Phendrin | 10 mg/5 ml | Syrup | Salton Pharmaceuticals Ltd. | ৳ 22.08 |
| Rymin | 10 mg/5 ml | Syrup | Opsonin Pharma Ltd. | ৳ 45.00 |
Indication DetailsView
Diphenhydramine is indicated for the treatment of followings:
- Seasonal, perennial, vasomotor rhinitis
- Urticaria, angioneurotic oedema, anaphylaxis
- Pruiritic conditions
- Premedication for emesis and motion sickness
- Miscellaneous like meniere's disease and parkinsonism
Therapeutic ClassView
Sedating Anti-histamine
PharmacologyView
Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.
DosageView
Adult-
- Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.
- 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
- More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day
Side EffectsView
Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.
ContraindicationsView
Known hypersensitivity to Diphenhydramine Hydrochloride, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.
PrecautionsView
Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.
InteractionsView
Diphenhydramine administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Diphenhydramine. Anticholinergic drugs may potentiate Diphenhydramine’s anticholinergic side effects.
Pregnancy & LactationView
Category B: There are no adequate and well controlled studies in pregnant women using diphenhydramine hydrochloride. Therefore, diphenhydramine hydrochloride should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended.
Overdose EffectsView
Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical).
Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.
Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.
Storage ConditionsView
Store between 15-30° C. Protect from moisture.