Dapagliflozin Propanediol
Generic / Active Ingredient
What is Dapagliflozin Propanediol used for?
Type 2 DM
10 Dapagliflozin Propanediol brands in Bangladesh
Compare prices across every brand of Dapagliflozin Propanediol and pick the most affordable option.
| Brand | Strength | Form | Manufacturer | Price |
|---|---|---|---|---|
| Dapaglip | 5 mg | Tablet | Incepta Pharmaceuticals Ltd. | ৳ 16.00 |
| Dapaglip | 10 mg | Tablet | Incepta Pharmaceuticals Ltd. | ৳ 30.00 |
| Daparol | 5 mg | Tablet | Drug International Ltd. | ৳ 12.00 |
| Dapawin | 5 mg | Tablet | Beacon Pharmaceuticals Ltd. | ৳ 16.00 |
| Dapazin | 5 mg | Tablet | Concord Pharmaceuticals Ltd. | ৳ 20.00 |
| Dapazin | 10 mg | Tablet | Concord Pharmaceuticals Ltd. | ৳ 30.00 |
| Diadap | 5 mg | Tablet | Opsonin Pharma Ltd. | ৳ 16.00 |
| Dialozin | 5 mg | Tablet | Jenphar Bangladesh Ltd. | ৳ 16.00 |
| Glycema | 5 mg | Tablet | ACI Limited | ৳ 16.00 |
| Glycema | 10 mg | Tablet | ACI Limited | ৳ 30.00 |
Indication DetailsView
Dapagliflozin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
Therapeutic ClassView
Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
PharmacologyView
Dapagliflozin is a highly potent, selective, and reversible inhibitor of sodium-glucose cotransporter 2 (SGLT2) that improves glycemic control in patients with type 2 diabetes mellitus by reducing renal glucose reabsorption leading to urinary excretion of excess glucose (glucuresis).
DosageView
5 mg orally once a day. May increase to 10 mg orally once a day in patients tolerating therapy with 5 mg and requiring additional glycemic control
Side EffectsView
Renal impairment, Female genital mycotic infections, Urinary tract infection, Increased urination, Male genital mycotic infections, Dyslipidemia, Constipation, Discomfort with urination, Extremity pain, Volume depletion, Hypersensitivity
ContraindicationsView
Hypersensitivity to dapagliflozin propanediol or to any of the excipients. Moderate to severe renal impairment; end-stage renal disease; active bladder cancer. Pregnancy (2nd & 3rd trimester) & lactation.
PrecautionsView
CV disease, history of hypotension, UTI, Children, Elderly. Unknown whether distributed in human breast milk; breastfeeding women should discontinue dapagliflozin or nursing taking into account the importance of the drug to the mother
InteractionsView
Hypoglycemia may occur with concomitant use with insulin & insulin secretagogues eg sulfonylureas. Decrease in Cmax & AUC with rifampin. Increase in Cmax & AUC with mefenamic acid. Increased thiazide & loop diuretic effects; may increase risk of dehydration & hypotension. Pioglitazone.
Pregnancy & LactationView
Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Pediatric UsageView
Renal Impairment: No dosage adjustment is indicated based on renal function. The efficacy is dependent on renal function. lt is not recommended for use in patients with moderate to severe renal impairment (patients with CrCI <60 mL/min or eGFR <60 mL/min/1.73 m2).