Clindamycin + Benzoyl peroxide
Generic / Active Ingredient
What is Clindamycin + Benzoyl peroxide used for?
Acne vulgaris
3 Clindamycin + Benzoyl peroxide brands in Bangladesh
Compare prices across every brand of Clindamycin + Benzoyl peroxide and pick the most affordable option.
| Brand | Strength | Form | Manufacturer | Price |
|---|---|---|---|---|
| Benoxiclin | 1%+5% | Topical Gel | UniMed UniHealth | ৳ 350.00 |
| Clindax-B | 1%+5% | Topical Gel | Opsonin Pharma Ltd. | ৳ 150.00 |
| Duac | 1%+5% | Topical Gel | GlaxoSmithKline | ৳ 698.00 |
Indication DetailsView
Indicated in acne vulgaris.
Therapeutic ClassView
Benzoyl peroxide, Azelaic acid & other preparations
PharmacologyView
Clindamycin is a semi-synthetic derivative of lincomycin. It inhibits bacterial protein synthesis by reversibly binding to the 50S ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms.
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its potent oxidizing activity. Clindamycin and Benzoyl peroxide are both active against Propionibacterium acnes, an organism associated with acne vulgaris.
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its potent oxidizing activity. Clindamycin and Benzoyl peroxide are both active against Propionibacterium acnes, an organism associated with acne vulgaris.
DosageView
Apply to the affected areas once or twice daily (morning and evening) after the skin is gently washed and patted dry.
Side EffectsView
Application site pain, Application site exfoliation, Application site irritation, Erythema, Burning, Pruritus, Sunburn, Scaling, Drynes, Colitis, Peelin.
ContraindicationsView
Hypersensitivity to Clindamycin, lincomycin, benzoyl peroxide, or any component of the formulation; history of regional enteritis, ulcerative colitis, pseudomembranous colitis or antibiotic-associated colitis.
PrecautionsView
Avoid contact with mouth, eyes, lips & mucous membranes; abraded or eczematous skin. May discolor hair & dyed fabrics. Pregnancy & lactation.
InteractionsView
May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding with vit K antagonists (e.g. warfarin, acenocoumarol, fluindione). PABA sunscreens may transiently discolour fabric.
Pregnancy & LactationView
Pregnancy Category- C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Lactation: Excretion in milk is unknown/ not recommended
Lactation: Excretion in milk is unknown/ not recommended
ReconstitutionView
Refer to individual product recommendations. Some combination products require reconstitution at the time of dispensing by dissolving the Clindamycin powder with purified water, add the solution to the Benzoyl peroxide gel provided and stir until the gel appears homogenous.